Oxidase ya Fructosyl-peptide (FPOX)
Ibisobanuro
Enzyme ni ingirakamaro mu kumenya fructosyl-peptide na aside fructosyl-L-amino.
Imiterere yimiti
Ihame ry'imyitwarire
Fructosyl-peptide + H.2O + O.2→ Peptide + Glucosone + H.2O2
Ibisobanuro
| Ibizamini | Ibisobanuro |
| Ibisobanuro | Ifu ya amorphous yera, lyofilize |
| Igikorwa | ≥4U / mg |
| Isuku (SDS-PAGE) | ≥90% |
| Catalase | ≤0.01% |
| ATPase | ≤0.005% |
| Glucose oxyde | ≤0.03% |
| Cholesterol oxyde | ≤0.003% |
Gutwara no kubika
Ubwikorezi: Ibidukikije
Ububiko:Ubike kuri -20 ° C (Igihe kirekire), 2-8 ° C (igihe gito)
Basabwe kongera gukora ikizaminiUbuzima:Imyaka 2
Amateka yiterambere
Kimwe mu bipimo bikoreshwa mu gusuzuma indwara ya diyabete ni glycated hemoglobine (HbA1c).Ibipimo bya HbA1c ukoresheje enzymes birakwiriye gutunganya umubare munini wikigereranyo, kandi birahendutse.Nkibyo, kuva kera harahamagarwa cyane nabashinzwe ubuzima kugirango bateze imbere iyo misemburo.Kubwibyo, twateje imbere ubushakashatsi bushya dukoresheje "uburyo bwa dipeptide".By'umwihariko, twavumbuye "Fructosyl-peptide Oxidase" (FPOX) ishobora gukoreshwa nka enzyme kuri iki kibazo.Ibi byaduteye gutsinda mugushikira iyambere kwisi dukora ukuri kwa enzyme ya HbA1c.Ubu buryo bwa "dipeptide" bukoresha Protease (enzyme ya Proteolytic) kugirango isenye HbA1c mumaraso, hanyuma igapima urwego rwa dipeptide ya sakariside yakozwe hakoreshejwe FPOX.Ubu buryo bwahuye nubwakire bwiza cyane kubera akamaro kabwo ko kuba bworoshye, buhendutse kandi bwihuse, kandi HbA1c gupima reagent ukoresheje FPOX ubu yatangiye gukoreshwa kwisi yose.
