Doxycycline Hyclate (24390-14-5)
Ibisobanuro ku bicuruzwa
● Doxycycline Hcl ni antibacterial spektr yegeranye cyane na Tetracycline na Terramycin, ariko ifite ingaruka nziza, witondere Staphylococcus Aureus ya tetracycline irwanya tetracycline, oxytetracycline, igihe kirekire.Bikunze gukoreshwa muri Senile Chronic Bronchitis, kwandura inzira zubuhumekero, kwandura ibihaha, acute tonillitis, mycoplasma pneumonia, kwandura inkari, kwanduza amaraso, bacillary dysentery, lymphadenitis acute, n'ibindi. Birazwi cyane ku barwayi ba Nephropathie kubera uburozi butagaragara ku mpyiko.
Hy Doxycycline Hyclate ni umunyu wa hyclate ya doxycycline, synthique, yagutse ya tetracycline antibiyotike yerekana ibikorwa bya mikorobe.Doxycycline hyclate ihuza bidasubirwaho na 30S ribosomal subunit, bishoboka ko na 50S ribosomal subunit nayo, bityo bikabuza guhuza aminoacyl-tRNA kumurongo wa mRNA-ribosome.Ibi biganisha ku kubuza intungamubiri za poroteyine.Mubyongeyeho, iyi agent yerekanye kubuza ibikorwa bya kolagenase.
Gusaba
Doxycycline Hyclate ikoreshwa mu kuvura indwara zitandukanye ziterwa na bagiteri, harimo n'izitera acne.Doxycycline Hyclate nayo ikoreshwa mukurinda malariya.Doxycycline Hyclate izwi nka antibiotique ya tetracycline.Ikora muguhagarika imikurire ya bagiteri.Iyi antibiotique ivura indwara ziterwa na bagiteri gusa.
| Ibintu | Ibisobanuro | Ibisubizo |
| Kugaragara | Ifu ya kristaline | Guhuza |
| Kumenyekanisha | TLC | Guhuza |
| acide sulfurike reaction ibara ry'umuhondo riratera imbere | Guhuza | |
| itanga reaction ya chloride | Guhuza | |
| PH | 2.0 ~ 3.0 | 2.3 |
| Kwinjira neza | kuri 349nm e (1%) 300 ~ 355 | 320 |
| Guhinduranya neza | -105 ~ -120 ° | -110 ° |
| Ibyuma biremereye: | ≤50ppm | <20ppm |
| Umwanda ukurura urumuri | kuri 490nm ≤0.07 | 0.03 |
| Ibintu bifitanye isano | 6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) ikindi kintu cyose cyanduye ≤0.5% bitamenyekanye umwanda ≤0.1% (ep5) | 1,6% 0.1% Ntibabonetse Ntibabonetse Ntibabonetse Ntibabonetse Ntibabonetse |
| Ethanol | 4.3 ~ 6.0% (m / m) | 4.5% |
| Ivu | ≤0.4% | 0,05% |
| Amazi | 1.4 ~ 2,8% | 1.8% |
| Suzuma | 95.0 ~ 102.0% (c22h25cln2o8) ishingiye kubintu bidafite imbaraga, bidafite Ethanol | 98,6% |
| Umwanzuro | Ihuze na USP32 | |
